• c-Jun
German: Jun
Japanese: Jun遺伝子

Molecular genetics. 1. c-Jun proteins are cellular DNA-binding proteins. They are produced by the c-jun genes in response to cell stimuli. c-Jun protein combines with c-Fos protein to form the AP-1 transcription factor that regulates the expression of many growth-related genes.

2. Proto-oncogene c-jun is one of the immediate early genes that are expressed in absence of de novo protein synthesis.

Notation: jun (italics) refers to the gene, Jun (first letter capitalized) to the protein. Prefix c- denotes the cellular form compared to v-, the viral form.

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