Study type: Therapeutical study (experimental study)

Effects of milimeter wave radiation on catalase activity. med./bio.

Published in: Electromagn Biol Med 2002; 21 (3): 303-308

Aim of study (acc. to author)

To examine whether microwaves would protect the activity of catalase in blood against the toxicity of cyclophosphamide (CPA), a commonly used anticancer drug.

Background/further details

Animals were irradiated before and after the administration of CPA.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 42.2 GHz
Modulation type: CW
Exposure duration: 30 min/d, 5 d/week for 3 weeks
  • SAR: 622 mW/g peak value (cf. remarks) (+/- 100 W/kg)
  • power density: 310 W/m² mean (+/- 5 mW/cm²)

Exposure 1

Main characteristics
Frequency 42.2 GHz
Type
Exposure duration 30 min/d, 5 d/week for 3 weeks
Additional info 42.2 GHz +/- 0.2 GHz.
Modulation
Modulation type CW
Exposure setup
Exposure source
Setup Animals restrained in cylindrical tubes (3.5 cm) in such a way that the midback was located under the Petri dish.
Additional info A 35 mm hole was cut on one side of the tube and a 35 mm petri dish was welded on the hole. A plastic ring around the horn was kept in contact with the Petri dish during exposure.
Parameters
Measurand Value Type Method Mass Remarks
SAR 622 mW/g peak value cf. remarks cf. remarks +/- 100 W/kg
power density 310 W/m² mean measured - +/- 5 mW/cm²

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Millimeter waves at 42.2 GHz and at the power levels commonly used in cancer therapy, before and after administration of CPA did not reduce the toxic effect of CPA on catalase activity in blood of mice.

Study character:

Study funded by