Study type: Medical/biological study (experimental study)

Are the conformational dynamics and the ligand binding properties of myoglobin affected by exposure to microwave radiation? med./bio.

Published in: Eur Biophys J 2003; 32 (7): 628-634

Aim of study (acc. to author)

To study the effects of microwaves on structural and functional properties of tuna myoglobin at 1.95 GHz, a frequency used by new wireless microwave communication systems.

Background/further details

In order to state safety guidelines it seems appropriate to start by excluding non-specific effects on dynamic and structural properties of fundamental biomolecules such as proteins (proteins are susceptible, in principle, to the action of electromagnetic fields).



Exposure Parameters
Exposure 1: 1.95 GHz
Modulation type: CW
Exposure duration: continuous for 2.5 h

Exposure 1

Main characteristics
Frequency 1.95 GHz
Exposure duration continuous for 2.5 h
Modulation type CW
Exposure setup
Exposure source
  • waveguide
  • 110 x 55 x 500 mm, surrounded by a thermostated water jacket
Setup The sample (3 ml of solution) in a polystyrene cuvette (10 x 10 x 35 mm) was placed vertically in the waveguide where the incident E field (vertical) was maximum.
Additional info The sample temperature at the beginning was 25 ± 0.1 °C, it increased to 30 ± 0.1 °C in about 30 min, and it remained at that value for the rest of the exposure period.
Measurand Value Type Method Mass Remarks
SAR 51 mW/g mean determined by power loss - ± 1 mW/g
electric field strength 197 V/m effective value calculated - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • after exposure

Main outcome of study (acc. to author)

The data indicate that, at least for the native state of the protein, microwave perturbation does not affect the structural organization of the myoglobin or its internal dynamics and CO binding affinity.

Study character:

Study funded by

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