Study type: Medical/biological study (experimental study)

Influence of 50 Hz frequency sinusoidal magnetic field on the blood-brain barrier permeability of diabetic rats. med./bio.

Published in: Bioelectromagnetics 2004; 25 (5): 400-402

Aim of study (acc. to author)

The aim of this study was to evaluate the influence of magnetic field exposure on the blood-brain barrier permeability in diabetic rats in contrast to normoglycemic rats.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: repeated daily exposure, 8 h/day for 21 consecutive days

General information

The experiment included 4 groups: group 1 (n=8) served as control, group 2 (n=8) normoglycemic + 50 Hz magnetic field, group 3 (n=8) diabetes mellitus and group 4 (n=12) diabetes mellitus + 50 Hz magnetic field.

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration repeated daily exposure, 8 h/day for 21 consecutive days
Exposure setup
Exposure source
Distance between exposed object and exposure source 0.012 m
Setup Animals from group 2 and 4 were injected with 65 mg/kg streptozotocin and were placed in cages which were placed above the coils. Animals from group 1 and 3 were held in the same conditions but the coils were not connected to the electric supply.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 5 mT effective value measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The findings of this study suggest that magnetic field has no effect on the blood-brain barrier permeability in normoglycemic animals. However, diabetic rats are vulnerable to magnetic fields.

Study character:

Study funded by

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