A surgical venous bypass model was used in this study to mimic many of the properties of the human disease. Mice were allowed to recover post operatively for 6 days. A total of 70 mice were used for the magnetic field/sham exposure. Mice were exposed to a 700 µT/50 Hz magnetic field for one week (10 animals), two weeks (10 animals), or three weeks (15 animals). An equivalent number of animals were sham exposed.
|magnetic flux density||700 µT||unspecified||measured||-||-|
Mice exposed for one week showed significantly smaller neointima formation (which means that the epidermal thickness of the venous bypass was reduced) as compared with sham exposed animals, although this effect was not observed in animals exposed for a longer period of time. Mononuclear cell infiltration and expression of heat shock protein 60 were not found to be altered due to magnetic field exposure.