To examine the effects of exposure to a static magnetic field (0.2 T) generated by a routinely used magnetic resonance tomograph on human skin fibroblasts. Changes in cell proliferation and cell morphology were evaluated.
| Exposure | Parameters |
|---|---|
|
Exposure 1:
Exposure duration:
continuous for 1 h
|
|
| Frequency | |
|---|---|
| Type | |
| Exposure duration | continuous for 1 h |
| Exposure source |
|
|---|---|
| Chamber | Magnetic unit / 121 cm high |
| Setup | Culture plates were placed in the isocenter of the magnet. Control cultures received the same treatment and were placed in a nearby room with identical temperature (26°C) and humidity conditions (60%) |
| Additional info | The tomograph was switched off during the experiment, hence there was no radio frequency generating images. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 200 mT | - | - | - | - |
The results showed that exposure to a static magnetic field (0.2 T) induced alterations on human skin fibroblasts in culture. The cell morphology was modified in association with the histochemically detected decrease in the expression of some sugar residues on the cell surface. The data showed a decrease of thymidine incorporation and of formation of mitogenic second messengers. However, cell viability was unaffected.
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