Study type: Medical/biological study (experimental study)

Effects of 0.2 T static magnetic field on human skin fibroblasts. med./bio.

Published in: Cancer Detect Prev 2003; 27 (5): 327-332

Aim of study (acc. to author)

To examine the effects of exposure to a static magnetic field (0.2 T) generated by a routinely used magnetic resonance tomograph on human skin fibroblasts. Changes in cell proliferation and cell morphology were evaluated.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Exposure duration: continuous for 1 h

Exposure 1

Main characteristics
Frequency
Type
Exposure duration continuous for 1 h
Exposure setup
Exposure source
Chamber Magnetic unit / 121 cm high
Setup Culture plates were placed in the isocenter of the magnet. Control cultures received the same treatment and were placed in a nearby room with identical temperature (26°C) and humidity conditions (60%)
Additional info The tomograph was switched off during the experiment, hence there was no radio frequency generating images.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 200 mT - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results showed that exposure to a static magnetic field (0.2 T) induced alterations on human skin fibroblasts in culture. The cell morphology was modified in association with the histochemically detected decrease in the expression of some sugar residues on the cell surface. The data showed a decrease of thymidine incorporation and of formation of mitogenic second messengers. However, cell viability was unaffected.

Study character:

Study funded by