Study type: Epidemiological study (observational study)

Magnetic field exposure and long-term survival among children with leukaemia. epidem.

Published in: Br J Cancer 2006; 94 (1): 161-164

Aim of study (acc. to author)

A cohort study was conducted in the USA to investigate the association between magnetic field exposure and survival among children with acute lymphoblastic leukaemia.

Further details

The event-free survival (the time from diagnosis to first treatment failure, relapse, secondary malignancy, or death) and the overall survival were evaluated to observe the progress of the disease.

Endpoint/type of risk estimation

Type of risk estimation: (event-free survival harzard ratio, survival)

Exposure

Assessment

Exposure groups

Group Description
Group 1 magnetic field exposure: < 0.1 µT
Group 2 magnetic field exposure: 0.1-0.19 µT
Group 3 magnetic field exposure: 0.2-0.29 µT
Group 4 magnetic field exposure: ≥ 0.3 µT

Population

Study size

Type Value
Total 1,672
Eligible 482
Participants 471
Evaluable 386
Other:

median duration of follow-up: 5.07 years

Statistical analysis method:

Conclusion (acc. to author)

The event-free survival harzard ratio for children with magnetic field measurements ≥ 0.3 µT was elevated (based on 5 cases): For overall survival, the hazard risk was significantly increased (based on 4 cases).

Limitations (acc. to author)

The small numbers (19 children exposed to magnetic field ≥ 0.3 µT ) limit inferences for the results.

Study funded by

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