Study type:
Epidemiological study
(observational study)
Are children living near high-voltage power lines at increased risk of acute lymphoblastic leukemia?
epidem.
By:
Kleinerman RA, Kaune WT, Hatch EE, Wacholder S, Linet MS, Robison LL, Niwa S, Tarone RE
Published in: Am J Epidemiol 2000; 151 (5): 512-515
Aim of study (acc. to author)
Further details
Children of the former study were included in the present study if they had been living in one home for at least 70 % of the reference period (5 years before diagnosis), and if measurements of the magnetic fields had been performed at the home. Magnetic field exposure was assessed by measuring the distance from the residence to high-voltage power lines and by calculating an exposure index based on distance and relative load for all transmission and three-phase distribution lines within 40 m of a house.
Endpoint/type of risk estimation
Type of risk estimation:
(odds ratio (OR))
Exposure
Assessment
- wire code: distance between subject's residence and all overhead transmission lines, three-phase primary distribution (thick or thin), first span secondary distribution lines and endpole lines passing within 40 m
- calculation: exposure index based on distance and relative load for all transmission and three-phase primary distribution lines within 40 m of a residence
Exposure groups
Group
|
Description
|
Reference group 1
|
distance to closest power line: > 40 m, mean magnetic field: 0.091 µT
|
Group 2
|
distance to closest power line: 24 - 40 m, mean magnetic field: 0.089 µT
|
Group 3
|
distance to closest power line: 15 - 23 m, mean magnetic field: 0.152 µT
|
Group 4
|
distance to closest power line: 0 - 14 m, mean magnetic field: 0.207 µT
|
Reference group 5
|
distance to closest transmission line: > 40 m, mean magnetic field: 0.103 µT
|
Group 6
|
distance to closest transmission line: 24 - 40 m, mean magnetic field: 0.067 µT
|
Group 7
|
distance to closest transmission line: 15 - 23 m, mean magnetic field: 0.130 µT
|
Group 8
|
distance to closest transmission line: 0 - 14 m, mean magnetic field: 0.279 µT
|
Reference group 9
|
distance to closest distribution line: > 40 m, mean magnetic field: 0.092 µT
|
Group 10
|
distance to closest distribution line: 24 - 40 m, mean magnetic field: 0.089 µT
|
Group 11
|
distance to closest distribution line: 15 - 23 m, mean magnetic field: 0.160 µT
|
Group 12
|
distance to closest distribution line: 0 - 14 m, mean magnetic field: 0.208 µT
|
Population
-
Group:
-
Age:
0–14 years
-
Observation period:
1989 - 1993
-
Study location:
USA (Illinios, Indiana, Iowa, Michigan, Minnesota, New Jersey, Ohio, Pennsylvania, Wisconsin)
Case group
Control group
- selected by random-digit telephone dialing
-
Matching:
Study size
|
Cases |
Controls |
Eligible |
851 |
825 |
Evaluable |
408 |
408 |
Statistical analysis method:
- conditional logistic regression
(
adjustment:
- age
- sex
- mother's educational level, and annual family income
)
Results (acc. to author)
Study funded by
Comments on this article
-
Bowman JD et al.
(2001):
Reply: "Are children living near high-voltage power lines at increased risk of acute lymphoblastic leukemia?"
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