Study type: Medical/biological study (experimental study)

Effects of Magnetic Field 0.1 and 0.05 mT on Leukocyte Adherence Inhibition med./bio.

By: Jandova A, Mhamdi L, Nedbalova M, Cocek A, Trojan S, Dohnalova A, Pokorny J
Published in: Electromagn Biol Med 2005; 24 (3): 283-292
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Aim of study (acc. to editor)

To study the effects of magnetic fields on cell-mediated immunity.

Background/further details

The main task of cell-mediated immunity is the reaction to foreign antigens on the surface of other cells. The cell-mediated immunity correlates with leukocytes cell adherence properties.
T lymphocytes taken from healthy humans and cancer patients before and after medical treatment (about 3-4 months after treatment) were exposed to the magnetic field.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 60 min
Exposure 2:
Exposure duration: continuous for 60 min

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuous for 60 min
Exposure setup
Exposure source
Setup Test tubes containing cell suspension were positioned in the center of the coil. For sham exposure, test tubes were placed in the same coil for the same amount but with no magnetic field.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.1 mT unspecified measured - -
magnetic flux density 0.05 mT unspecified measured - -
Measurement and calculation details

Magnetic field was measured by Gauss and Tesla meter with Hall probes.

Exposure 2

Main characteristics
Frequency
Type
Exposure duration continuous for 60 min
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.1 mT unspecified measured - -
magnetic flux density 0.05 mT unspecified measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Magnetic field exposures increased the adherence of T lymphocytes, especially those from cancer patients before medical treatment. The effects of the magnetic field exposures at 0.1 and 0.05 mT were similar to those of stronger magnetic fields in the range of 0.5 to 10 mT. The effects of the AC and DC magnetic fields at 0.05 mT did not display large differences attributable to the magnetic field.

Study character:

Study funded by

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