Study type: Medical/biological study (experimental study)

Accelerated development of spontaneous and benzopyrene-induced skin cancer in mice exposed to 2450-MHz microwave radiation. med./bio.

Published in: Bioelectromagnetics 1982; 3 (2): 179-191

Aim of study (acc. to author)

To demonstrate the acceleration of development of spontaneous and chemically induced tumors and the lowering of natural antineoplastic resistence in mice exposed to 2450 MHz during 1-6 months.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: 2 h/d, 6 sessions/week, upto 230 days.

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Charakteristic
Exposure duration 2 h/d, 6 sessions/week, upto 230 days.
Modulation
Modulation type CW
Exposure setup
Exposure source
Distance between exposed object and exposure source 2.2 m
Chamber polymethacrylate cages/ 20 cm x 30 cm x 10 cm.
Setup Animals were kept in cages containing 20 transparent compartments 5 cm x 6 cm x 10 cm each in the anechoic chamber.
Parameters
Measurand Value Type Method Mass Remarks
power density 50 W/m² mean measured - SAR 2-3 mW/g calculated value.
power density 150 W/m² mean measured - SAR 6-8 mW/g calculated value.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Irradiation with microwaves (5 or 15mW/cm²) for 3 months resulted in a significant lowering of natural antineoplastic resistence and acceleration of development of benzpyrene-induced skin cancer. Microwave-exposed C3H/HeA mice developed breast tumors earlier than control mice. A similar acceleration was observed in the development of benzpyrene-induced skin cancer in animals exposed simultaneously to benzpyrene and microwaves. The acceleration of cancer development in all systems and lowering of natural antineoplastic resistence was similar in mice exposed to microwaves at 5 mW/cm² or to chronic stress caused by confinement but differed significantly from the data obtained on mice exposed to 15 mW/cm², where thermal effects were possible.

Study character:

Study funded by

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