Study type: Medical/biological study (experimental study)

Intermediate frequency magnetic fields generated by an induction heating (IH) cooktop do not affect genotoxicities and expression of heat shock proteins. med./bio.

Published in: Int J Radiat Biol 2009; 85 (10): 883-890

Aim of study (acc. to author)

To evaluate the effects of intermediate frequency magnetic fields generated by induction heating cooktops on cellular genotoxicity and stress responses.

Background/further details

Different cell lines were used for different endpoints. For positive controls, the cells were exposed to 2 Gy X rays (for cell growth), to bleomycin (for micronucleus formation), to ethylmethansulfonate (for HPRT assay), or to heat (for heat shock protein expression).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 23 kHz
Exposure duration: continuous for 2 hr

Exposure 1

Main characteristics
Frequency 23 kHz
Type
Waveform
Exposure duration continuous for 2 hr
Exposure setup
Exposure source
Setup 35 cm high solenoid coil (outer diameter = 45 cm, inner diameter = 29 cm) with 96 turns of insulated copper wire; coil with cooling system placed inside an incubator; culture dishes stacked in four layers and positioned in the center of the coil in the 9.5 cm high exposure area of 10 cm diameter
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 6.05 mT effective value measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The data did not detect any effects of the intermediate frequency magnetic fields on cell growth, comet assay, micronucleus formation, HPRT gene mutation, expression of phosphorylated Hsp27, or nuclear translocation of Hsp27, Hsp70 or Hsp105. In conclusion, the data indicate that exposure to an intermediate frequency magnetic field at 6.05 mT(rms-value) for 2 h does not cause detectable cellular genotoxicity, and does not induce detectable cellular stress.

Study character:

Study funded by

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