Study type: Epidemiological study (observational study)

Occupation and risk of glioma, meningioma and acoustic neuroma: results from a German case-control study (interphone study group, Germany). epidem.

Published in: Cancer Epidemiol 2010; 34 (1): 55-61

Aim of study (acc. to author)

The association between six a priori defined occupational sectors (chemical, metal, agricultural, construction, electrical/electronic and transport) and the risk of glioma, meningioma and acoustic neuroma was investigated in the German part of the Interphone Study.

Further details

Job activities were coded according to the International Standard Classification of Occupations 1988 (ISCO 88).
Occupational exposures to radiofrequency electromagnetic fields were investigated in Berg et al 2006 and therefore are not included in the present publication.

Endpoint/type of risk estimation

Type of risk estimation: (odds ratio (OR))

Exposure

Assessment

Exposure groups

Group Description
Reference group 1 participants with no activity in the six occupational sectors
Group 2 electrical/electronics occupational sector

Population

Case group

Control group

Study size

Cases Controls
Participants 844 1,688
Other:

366 glioma cases, 381 meningioma cases, 87 acoustic neuroma cases

Statistical analysis method: (adjustment: )

Conclusion (acc. to author)

No increased risks for glioma and meningioma were observed among participants with occupational activities in the electricity/electronics area. An increased risk for acoustic neuroma was found for participants with occupation duration of five years or more in the electrical/electronic sector (OR 3.39, CI 1.03-11.10). However this result may be due to chance because it is based on small numbers (8 cases and 9 controls).
The authors concluded that no increased risk of glioma, meningioma and acoustic neurima was observed in individuals who have ever worked in the chemical, metal, agricultural, construction, electrical/electronic and transport sectors.

Study funded by

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