Study type: Medical/biological study (experimental study)

Effect of pulsed electromagnetic fields on human tenocyte cultures from supraspinatus and quadriceps tendons. med./bio.

Published in: Am J Phys Med Rehabil 2011; 90 (2): 119-127

Aim of study (acc. to author)

To study the effects of pulsed electromagnetic fields (PEMFs) on human tenocyte cultures and to assess whether PEMFs could represent a viable therapeutic option in tendon pathologies.

Background/further details

Human tenocytes (primary cells) were isolated from healthy supraspinatus and quadriceps tendons during shoulder arthroscopy (of six patients).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 12, 24, 36, 72 h, 5 days, 7 days or 14 days

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuous for 12, 24, 36, 72 h, 5 days, 7 days or 14 days
Exposure setup
Exposure source
Setup 30 cm long solenoid with a diameter of 15 cm and 45 turns of 20-gauge magnetic wire
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.4 mT - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Tenocyte growth, cell cycle, cell morphology analysis, and total collagen accumulation did not show any statistically significant differences between exposed groups and control groups. However, exposure to PEMF significantly accelerated cut closure at 12 and 24 h after the injury.

Study character:

Study funded by

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