Study type: Medical/biological study (experimental study)

Investigation of the effects of 50 Hz magnetic fields on platelet aggregation using a modified aggregometer. med./bio.

Published in: Electromagn Biol Med 2012; 31 (4): 382-393

Aim of study (acc. to author)

To study whether 50 Hz magnetic fields (1 mT and 6 mT) have any effects on platelet aggregation.

Background/further details

Blood from 80 healthy volunteers was anti-coagulated with either sodium citrate or heparin (n=40 each). Each sample was divided in an exposed and a sham exposed sample. Adenosine diphosphate, collagen, and epinephrine were used as aggregation inducing agents. 60 samples (30 sodium citrate, 30 heparin) were exposed at 1 mT, 20 samples were exposed at 6 mT (10 sodium citrate, 10 heparin).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous for 1.5 h
Exposure 2: 50 Hz
Exposure duration: continuous for 1 h

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 1.5 h
Exposure setup
Exposure source
Setup two coils were connected in series; coils were built using a 2 mm copper wire wound on a circular frame of 50 cm diameter (350 turns in each coil)
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 1 mT - measured - ± 0.05 mT (at the center of the coils)

Exposure 2

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous for 1 h
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 6 mT - - - ± 0.05 mT (at the center of the coils)

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Exposure to a 1 mT 50 Hz magnetic field for 1.5 h had a significant effect on the aggregation parameters of collagen-induced aggregation in sodium citrate treated samples: the maximum values and slope of the collagen-induced aggregation curve were significantly increased. No significant differences were found in any other group.

Study character:

Study funded by

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