Study type: Medical/biological study (experimental study)

Radiofrequency radiation-induced calcium ion efflux enhancement from human and other neuroblastoma cells in culture. med./bio.

Published in: Bioelectromagnetics 1989; 10 (2): 197-202

Aim of study (acc. to author)

To test the generality of radiofrequency radiation-induced changes in 45Ca2+ efflux from avian and feline brain tissues, human neuroblastoma cells were exposed to electromagnetic radiation.



Exposure Parameters
Exposure 1: 147 MHz
Modulation type: AM
Exposure duration: 30 min

Exposure 1

Main characteristics
Frequency 147 MHz
Exposure duration 30 min
Modulation type AM
Modulation frequency 16 Hz
Modulation depth 80 %
Exposure setup
Exposure source
Chamber Incubator maintained at 37°
Setup Two flasks were placed inside the Crawford cell
Additional info Two other flasks were placed outside the Crawford cell but in the same incubator which served as control. SAR was determined from incident, reflected and transmitted power measured with 1) an empty Crawford cell 2) a Crawford cell with an empty flask 3) a Crawford cell and flask with culture and 5 ml of growth medium.

No parameters are specified for this exposure.

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Significant 45Ca2+ efflux was obtained at SAR values of 0.05 and 0.005 W/kg. Chinese hamster-mouse hybrid neuroblastoma cells were also shown to exhibit enhanced radiation-induced 45Ca2+ efflux at a SAR of 0.05 W/kg. The results confirm that amplitude-modulated radiofrequency exposition can induce responses in cells of nervous tissue origin from widely different animal species, including humans. The findings are also consistent with the reports of similar findings in avian and feline brain tissue and indicate the general nature of the phenomen.

Study character:

Study funded by

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