Study type: Medical/biological study (experimental study)

Developmental studies of Hanford miniature swine exposed to 60-Hz electric fields. med./bio.

Published in: Bioelectromagnetics 1987; 8 (3): 229-242

Aim of study (acc. to author)

To examine wether exposure of swines to 60 Hz-electric fields has an effect on reproductive, developmental and teratologic endpoints.

Background/further details

The first generation (P1) of gilts (31 exposed, 18 sham exposed) was mated after 4 month of the experiment with unexposed boars. Some of them were killed at day 100 of gestation (teratological examination I), the others produced a F1 generation of offspring (litter I). The P1 sows which produced the F1 generation were mated again after 10 month of exposure/sham exposure and were killed at day 100 of gestation (teratological examination II). The F1 gilts (29 exposed, 14 sham exposed) were mated at the age of 18 month (litter II) and again 10 month later, but then killed at day 100 of gestation (teratological examination III).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 60 Hz
Exposure duration: 20 h/day, 7 days/week

Exposure 1

Main characteristics
Frequency 60 Hz
Type
Exposure duration 20 h/day, 7 days/week
Exposure setup
Exposure source
  • not specified
Setup exposed and shamexposed swines were housed in separate, equivalent buildings; average daily temperatures and relative humidities in both buildings were similar (23°C and 40%, respectively)
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 30 kV/m unspecified measured - -

Reference articles

  • Kaune WT et al. (1980): Comparison of the coupling of grounded humans, swine and rats to vertical, 60-Hz electric fields.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

No significant differences occurred in malformation incidence, litter size, fetal mass or mass of fetal organs between the first offspring of the exposed and the sham exposed P1-sows (litter I + teratological examinations I). However, a greater malformation incidence was found in the second offspring of the exposed P1-sows, but no differences in litter size, fetal mass or mass of fetal organs were observed when compared to the sham exposed P1-sows(teratological examinations II). In the first offspring of the exposed F1-sows significantly more malformations were found than in the first offspring of the sham exposed F1-sows (litter II). However, no significant difference in the number of malformations was found between the second offspring of the exposed F1-sows and the second offspring of the sham exposed F1-sows (teratological examinations III).
The authors conclude that there could be an association between exposure to a 60 Hz-electric field and malformations in the offspring of swine, though a number of potentially interacting factors may be involved in the responses, too.

Study character:

Related articles