Study type: Medical/biological study (experimental study)

A novel method for the study of fluorescent probes in biological material during exposure to microwave radiation. med./bio.

Published in: J Biochem Biophys Methods 1981; 5 (3): 157-167
Journal partially peer-reviewed/unclear

Aim of study (acc. to author)

To investigate the effect of 2450 MHz CW microwave irradiation on calcium binding to erythrocyte ghosts. For this approach the fluorescent probe ANS (1-anilino-8-naphthalene sulfonate) was used.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: continuous 10 min
  • SAR: 10 mW/g minimum (center of stirred solution)
  • SAR: 200 mW/g maximum (center of stirred solution)

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Polarization
Exposure duration continuous 10 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Chamber waterfilled
Parameters
Measurand Value Type Method Mass Remarks
SAR 10 mW/g minimum measured - center of stirred solution
SAR 200 mW/g maximum measured - center of stirred solution

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

Overall no effects were observed. Neither specific absorption rates of 10 and 200 mW/g nor calcium doses between 2.0 and 10.0 x10-4 M had any effect on binding of ANS to the erythrocyte ghosts or calcium binding, respectively. Also the intrermolecular distances between membrane bound ANS and intrinsic tryptophan residues were not altered.

Study character:

Study funded by