Study type: Medical/biological study (experimental study)

Influence of microwaves on different types of receptors and the role of peroxidation of lipids on receptor-protein shedding. med./bio.

Published in: Bioelectromagnetics 1994; 15 (3): 183-192

Aim of study (acc. to author)

To investigate the effects of microwave exposure of rat chemoreceptors in vitro. In this context also the role of lipid peroxidation on protein shedding was examined.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: CW
Exposure duration: continuous for 15 min
  • SAR: 18 W/kg mean (0.5, 1, 4, 12, and 18 W/kg)
  • SAR: 90 W/kg peak value (2.5-90 W/kg)
Exposure 2: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 15 min
  • SAR: 18 W/kg mean (0.5, 1, 4, 12, and 18 W/kg)
  • SAR: 90 W/kg peak value (2.5-90 W/kg)

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 15 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Chamber A steady-state exposure temperature of 4 °C was achieved by water circulating around the glass exposure tube.
Additional info In most of the experiments, samples were exposed for 15 min.
Parameters
Measurand Value Type Method Mass Remarks
SAR 18 W/kg mean measured and calculated - 0.5, 1, 4, 12, and 18 W/kg
SAR 90 W/kg peak value measured and calculated - 2.5-90 W/kg

Exposure 2

Main characteristics
Frequency 900 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 15 min
Modulation
Modulation type pulsed
Duty cycle 20 %
Repetition frequency 100 Hz
Pulse type rectangular
Additional info

Pulse repetition rate was 1, 6, 16, 32, 75, or 100 pps.

Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
SAR 18 W/kg mean measured and calculated - 0.5, 1, 4, 12, and 18 W/kg
SAR 90 W/kg peak value measured and calculated - 2.5-90 W/kg

Reference articles

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Microwave exposure affected the ligand/cell membrane binding in different manner. The binding of glutamic acid to hippocampal cells was not altered, whereas the binding of dihydroalprenolol to liver cell membranes was fivefold decreased. Also the binding of camphor to the olfactory membrane fraction was decreased up to 80%. Microwave exposure did not cause an accumulation of products from the lipid peroxidation.

Study character:

Study funded by