Study type: Medical/biological study (experimental study)

The effect of 2450-MHz microwave radiation during microtubular polymerization in vitro med./bio.

By: Ortner MJ, Galvin MJ, Irwin RD
Published in: Radiat Res 1983; 93 (2): 353-363
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Aim of study (acc. to author)

To investigate the effects on the dynamics (on three critical stages of the intracellular polymerization cycle) of microtubule formation during microwave irradiation in vitro. In addition the effects on the secondary structure were studied after irradiation.

Background/further details

The first approach was obtained by light scattering measurements of dissolved protein using the turbidity as an index of polymerization. The second approach was obtained by circular dichroism.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: continuous for 10 min
  • SAR: 200 mW/g maximum (unspecified)
  • SAR: 20 mW/g minimum (unspecified)

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration continuous for 10 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Additional info In both exposed and control samples the temperature was maintained at 37°C ± 0.3°C.
Parameters
Measurand Value Type Method Mass Remarks
SAR 200 mW/g maximum - unspecified -
SAR 20 mW/g minimum - unspecified -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Microwave irradiation had no effects on the polymerization or depolymerization of microtubulin proteins in vitro. Furthermore the irradiation had no effect on the secondary structure as determined by circular dichroism.

Study character:

Study funded by

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