Study type: Medical/biological study (experimental study)

In vitro testing of cellular response to ultra high frequency electromagnetic field radiation. med./bio.

Published in: Toxicol In Vitro 2008; 22 (5): 1344-1348

Aim of study (acc. to author)

The aim of this study was to evaluate whether low-level, ultrahigh frequency irradiation of 935 MHz influences the cell structure and growth of lung fibroblasts of the Chinese hamster.

Background/further details

Colchicine treated cells were the positive controls.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 935 MHz
Modulation type: CW
Exposure duration: continuous for 1, 2, and 3 h

Exposure 1

Main characteristics
Frequency 935 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 1, 2, and 3 h
Modulation
Modulation type CW
Exposure setup
Exposure source
Chamber Temperature inside the GTEM cell was measured every 10 min and maintained at 37 °C.
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 8.2 V/cm - - - ± 0.3 V/cm
SAR 0.12 W/kg mean calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Structural differences apparent in grainy fluorescent clusters comparable to those found in positive control cells were observed in cells exposed for 3 hours. These grainy structures suggest that microtubule fibers are highly dissipated.
Significantly decreased growth was seen in cells exposed for 3 hours three days after irradiation.
These results indicate that the 935 MHz, low-level ultrahigh frequency irradiation for 3 hours affects microtubule proteins, which consequently may obstruct cell growth.

Study character:

Study funded by

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