Study type: Medical/biological study (experimental study)

Cardiovascular and thermal effects of microwave irradiation at 1 and/or 10 GHz in anesthetized rats. med./bio.

Published in: Bioelectromagnetics 2000; 21 (3): 159-166

Aim of study (acc. to author)

To determine the thermal distribution and cardiovascular effects of sustained exposure to 1-GHz, 10-GHz, or combined 1- and 10-GHz irradiation, in both E (left lateral exposure, long axis parallel to the electric field) and H (left lateral exposure, long axis perpendicular to the electric field) orientation.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 1 GHz
Modulation type: CW
Exposure duration: until death; 25.6 +/- 1.2 min
Exposure 2: 10 GHz
Modulation type: CW
Exposure duration: until death; 34.7 +/- 1.1 min
Exposure 3: 10 GHz
Modulation type: CW
Exposure duration: until death; 30.5 +/- 1.4 min
Exposure 4: 1 GHz
Modulation type: CW
Exposure duration: until death; 28.5 +/- 0.7 min
  • power density: 105 mW/cm² unspecified
  • SAR: 12 W/kg mean (whole body) (determined calorimetrically)
Exposure 5: 10 GHz
Modulation type: CW
Exposure duration: until death; 34.3 +/- 0.5 min
Exposure 6: 10 GHz
Modulation type: CW
Exposure duration: until death; 29.7 +/- 0.1 min

Exposure 1

Main characteristics
Frequency 1 GHz
Charakteristic
Exposure duration until death; 25.6 +/- 1.2 min
Modulation
Modulation type CW
Exposure setup
Exposure source
  • not specified
Additional info Left lateral exposure, long axis parallel to the electric field.
Parameters
Measurand Value Type Method Mass Remarks
power density 380 W/m² unspecified unspecified - -
SAR 12 W/kg mean cf. remarks whole body determined calorimetrically

Exposure 2

Main characteristics
Frequency 10 GHz
Charakteristic
Exposure duration until death; 34.7 +/- 1.1 min
Modulation
Modulation type CW
Exposure setup
Exposure source
  • not specified
Additional info Left lateral exposure, long axis parallel to the electric field.
Parameters
Measurand Value Type Method Mass Remarks
power density 670 W/m² unspecified unspecified - -
SAR 12 W/kg mean cf. remarks whole body determined calorimetrically

Exposure 3

Main characteristics
Frequency 10 GHz
Charakteristic
Exposure duration until death; 30.5 +/- 1.4 min
Additional info Simultaneous 1 GHz and 10 GHz exposure.
Modulation
Modulation type CW
Exposure setup
Exposure source
  • not specified
Additional info Left lateral exposure, long axis parallel to the electric field.
Parameters
Measurand Value Type Method Mass Remarks
power density 335 W/m² unspecified unspecified - at 10 GHz.
power density 193 W/m² unspecified unspecified - at 1 GHz
SAR 12 W/kg mean cf. remarks whole body determined calorimetrically

Exposure 4

Main characteristics
Frequency 1 GHz
Charakteristic
Exposure duration until death; 28.5 +/- 0.7 min
Modulation
Modulation type CW
Exposure setup
Exposure source
  • not specified
Additional info Left lateral exposure, long axis perpendicular to the electric field.
Parameters
Measurand Value Type Method Mass Remarks
power density 105 mW/cm² unspecified unspecified - -
SAR 12 W/kg mean cf. remarks whole body determined calorimetrically

Exposure 5

Main characteristics
Frequency 10 GHz
Charakteristic
Exposure duration until death; 34.3 +/- 0.5 min
Modulation
Modulation type CW
Exposure setup
Exposure source
  • not specified
Additional info Left lateral exposure, long axis perpendicular to the electric field.
Parameters
Measurand Value Type Method Mass Remarks
power density 580 W/m² unspecified unspecified - -
SAR 12 W/kg mean cf. remarks whole body determined calorimetrically

Exposure 6

Main characteristics
Frequency 10 GHz
Charakteristic
Exposure duration until death; 29.7 +/- 0.1 min
Additional info Simultaneous 1 GHz and 10 GHz exposure.
Modulation
Modulation type CW
Exposure setup
Exposure source
  • not specified
Additional info Left lateral exposure, long axis parallel to the electric field.
Parameters
Measurand Value Type Method Mass Remarks
power density 525 W/m² unspecified unspecified - at 1 GHz
power density 290 W/m² unspecified unspecified - at 10 GHz.
SAR 12 W/kg mean cf. remarks whole body determined calorimetrically

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

In both E and H orientations, survival time was lowest in animals exposed to 1-GHz and greatest in the 10-GHz group. Temperature values in the 1- and 10-GHz combined group were between those of the single-frequency exposure groups in both orientations. During irradiation, arterial blood pressure initially increased and then decreased until death. Heart rate increased throughout the exposure time. The results indicate that no unusual physiological responses occur due to multifrequency microwave exposure, when compared to results of single-frequency exposure.

Study character:

Study funded by

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