The parasite protozoans Trichomonas vaginalis and Giardia lamblia were investigated in view of a potential therapeutic use in antimicrobial treatments. The following groups were used (27 cultures per group): 1) exposure to the magnetic field, 2) control group, 3) treatment of cells with Metronidazole (a well-known anti-parasite drug) at 0.14 μg/ml for T. vaginalis and 0.56 μg/ml for G. lamblia as positive controls, 4) co-exposure of cells to the magnetic field and Metronidazole.
|Setup||the exposure device comprised a coil that was built by winding 340 turns of 1.3 mm diameter enamel insulated copper wire to form a cylindrical solenoid with a radius of 5.27 cm and a length of 25 cm; the frequency content of the magnetic field was nearly pure 60 Hz (<3% total harmonic distortion); a plastic separator was placed inside the solenoid to allow the placement of cultures in predetermined zones where the magnetic field was homogeneous|
|Additional info||exposure started when cells reached the end of logarithmic phase|
In T. vaginalis, exposure to the magnetic field (group 1) signficantly reduced the number of cells compared to the control group (group 2). In G. lamblia, however, exposure to the magnetic field significantly increased the number of cells compared to the control group. In both protozoa, treatment with Metronidazole (group 3) significantly decreased the number of cells compared to the control group and there were no significant differences compared to the Metronidazole and magnetic field co-exposure group (group 4). This indicated an absence of a synergistic or antagonistic effect.
The authors conclude that exposure to a 50 Hz magnetic field might affect growth in two human parasite protozoans but without indications for a therapeutic use.