Study type: Medical/biological study (experimental study)

Hypothermia and electromagnetic rewarming in the rhesus monkey. med./bio.

Published in: Aviat Space Environ Med 1984; 55 (12): 1111-1117

Aim of study (acc. to author)

To evaluate the effectiveness and safety of using radiofrequency energy to rewarm hypothermic casualties.

Background/further details

Following hypothermia induction, monkeys were rewarmed using either a ventrally applied surgical heating pad supplied with 35°C water (control group) or a radiofrequency induction coil operating at 13.56 MHz.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 13.56 MHz
Exposure duration: 1 h

Exposure 1

Main characteristics
Frequency 13.56 MHz
Type
Exposure duration 1 h
Exposure setup
Exposure source
Chamber Insulated acrylic box/ 60 cm x 60cm x 129 cm
Setup Subjects were restrained in the supine position in a formed plastic couch.
Parameters
Measurand Value Type Method Mass Remarks
SAR 5.5 mW/g mean calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Radiofrequency rewarming to 35°C typically required only 50 min, whereas an average of 137 min was required for heating-pad rewarming. Analyses of blood serum collected during and after hypothermia treatments showed elevations at 24 h in creatine phosphokinase, lactate dehydrogenase, and glutamic oxaloacetic transaminase (enzyme level determinations are a primary tool to assess possible internal tissue injury). These elevations were highest for the controls and lowest for the radiofrequency rewarming experiments.
It is concluded that the careful application of radiofrequency energy to the central core of the body can successfully be used for rewarming purposes and it is more effective than externally applied rewarming techniques.

Study character:

Study funded by

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