In a previous study (publication 673), it was found that sodium dependent high-affinity choline uptake in the hippocampus and frontal cortex of rats was lowered after acute exposure to low-level 2450 MHz pulsed microwaves. In the present study, the authors investigated developments of tolerance and classical conditioning to these effects of microwaves.
|Pulse width||2 µs|
|Repetition frequency||500 Hz|
|Setup||Four rats were simultaneously subjected to MW or sham exposure.|
|Sham exposure||A sham exposure was conducted.|
|Additional info||On the 11th day, both MW and sham exposed rats were randomly assigned to another MW or sham session. In addition, some rats were not put in the waveguides. So, there were six treatment groups in total regarding 10-day and 11th-day exposures.|
The authors found that tolerance, a decrease in response to microwaves, developed to the effect of microwaves on choline uptake in the hippocampus, but not in the frontal cortex. Conditioned effects were also found: an increase in choline uptake in the hippocampus and a decrease in uptake in the frontal cortex. The results suggest that the effects of microwaves on choline uptake in the hippocampus and frontal cortex are classically conditionable, probably to cues in the exposure environment.