Study type: Medical/biological study (experimental study)

Slow potentials and spike unit activity of the cerebral cortex of rabbits exposed to microwaves med./bio.

Published in: Bioelectromagnetics 1988; 9 (4): 337-345

Aim of study (acc. to author)

To analyze the evoked activity and driving response in the cerebral cortex during EEG reactions and to determine if changes in the neuronal activity occur in response to microwaves.

Background/further details

Slow potentials and spike unit activity were investigated. The analysis involved consideration of 1) the background activity, 2) the evoked response to single light flashes, and 3) the evoked response to sequences of light flashes of increasing intensity or increasing frequency (driving response).

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Modulation type: CW
Exposure duration: 1 min/measurement
Exposure 2:
Modulation type: CW
Exposure duration: 1 min

Exposure 1

Main characteristics
Type
Waveform
Exposure duration 1 min/measurement
Modulation
Modulation type CW
Exposure setup
Exposure source
  • Cylindrical irradiating unit
Distance between exposed object and exposure source 0.1 m
Setup animals restrained in wooden frame, with the long axis of the animal parallel to the vector E.
Additional info In the control experiments the biopotential were registered under similar conditions, but without microwave exposure.
Parameters
Measurand Value Type Method Mass Remarks
power density 400 W/m² unspecified measured - -

Exposure 2

Main characteristics
Type
Waveform
Exposure duration 1 min
Modulation
Modulation type CW
Exposure setup
Exposure source
  • LUCH-58 generator with cylindrical irradiating unit
Distance between exposed object and exposure source 0.1 m
Setup rabbits restrained in wooden frame
Additional info Exposure setup not described in detail. Type of antenna non-standard (ittem in corresponding field of data base thus not correct). Determination of power density unknown.
Parameters
Measurand Value Type Method Mass Remarks
power density 400 W/m² unspecified measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

A 1-min microwave exposure of the animals head produced an EEG response by an increased number of spindle-shape firings and slow waves. These were accompanied by a change in pulse frequency of neurons, an increase in some cells and a decrease in other cells.
After microwave irradiation an enhancement of evoked responses was observed in the visual cortex neurons to single light flashes in 61% of the cases. The microwave fields facilitated the driving response to light flashes in 80% of cases. This was evidenced by a decreased threshold for obtaining evoked potentials and widening of the frequency range to which neurons were able to respond.
The evoked activity was a more sensitive indicator of the radiofrequency electromagnetic field effect than background activity. The reactivity alterations were more easily detected when using the driving response test than by using single stimuli.

Study character:

Study funded by

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