Study type: Medical/biological study (observational study)

Comparison of chromosome aberrations in peripheral blood lymphocytes from people occupationally exposed to ionizing and radiofrequency radiation. med./bio.

Published in: Acta Med Okayama 2001; 55 (2): 117-127

Aim of study (acc. to author)

In an attempt to correlate the genotoxic effects of non-ionizing and ionizing radiation, a chromosome aberration analysis of peripheral blood lymphocytes in 20 individuals, who were working in Croatian radio-relay stations was performed. Cells from 25 physicians and nurses who had been regularly exposed to ionizing radiation was also studied.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 0 Hz–8 GHz
Exposure duration: 5 to 38 years

Exposure 1

Main characteristics
Frequency 0 Hz–8 GHz
Type
Exposure duration 5 to 38 years
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
power density 10 W/m² maximum - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results demonstrate that total number of chromosome aberrations in people exposed to ionizing or radiofrequency radiation (4.08 +/- 0.37 and 4.35 +/- 0.5 on 200 scored metaphases, respectively) were almost equally higher than those of non irradiated subjects. Acentric fragments were the most frequently seen type of aberration. The average numbers in examined groups (11.8 x 10-3 and 14.8 x 10-3 per cell, respectively), were significantly higher than 4.2 x 10-3, which was observed in unexposed individuals. Dicentric fragments were also frequent (4.8 x 10-3 and 6.25 x 10-3, respectively, vs. 0.52 x 10-3 in unexposed subjects). In contrast, the frequency of chromatid breaks increased only after ionizing radiation (3.8 x 10-3 vs. 0.26 x 10-3 in control).

Study character:

Study funded by

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