Medical/biological study (observational study)

Effect of mobile phone station on micronucleus frequency and chromosomal aberrations in human blood cells med./bio.

By: Yildirim MS, Yildirim A, Zamani AG, Okudan N

Published in: Genet Couns 2010; 21 (2): 243-251

Journal partially peer-reviewed/peer-review process unclear

PubMed

Aim of study (acc. to author)

To evaluate the effects of mobile phone base stations on the micronucleus frequency and chromosomal aberrations in blood of people who were living around mobile phone base stations (n=14) and of controls who lived away from base stations (n=14).

Background/further details

The study group consisted of 14 volunteers who lived in the penthouse flat of 10 buildings with base station antennas on the roofs.

Endpoint

genotoxicity/mutation: micronucleus formation and chromosome aberrations in lymphocytes

Exposure

- low level microwaves
- mobile communications
- mobile phone base station
- not extractable

No exposure details are available.

Exposed system:

human
whole body

Methods Endpoint/measurement parameters/methodology

genotoxicity/mutation: micronucleus formation (frequency; Giemsa staining and light microscopy) and chromosome aberration (conventional metaphase analysis)

Investigated system:

DNA/RNA
blood samples

Time of investigation:

after exposure

Main outcome of study (acc. to author)

The data did not show any significant difference in micronucleus frequency and chromosome aberrations between the two groups. The results indicate that cellular phones and their base stations do not produce important carcinogenic changes.

Study character:

medical/biological study
observational study
full/main study

Study funded by

not stated/no funding

Gandhi G et al. (2015): A cross-sectional case control study on genetic damage in individuals residing in the vicinity of a mobile phone base station
Souza LCM et al. (2014): Assessment of nuclear abnormalities in exfoliated cells from the oral epithelium of mobile phone users
Sekeroglu V et al. (2012): Cytotoxic and genotoxic effects of high-frequency electromagnetic fields (GSM 1800MHz) on immature and mature rats
Ros-Llor I et al. (2012): Effect of mobile phones on micronucleus frequency in human exfoliated oral mucosal cells
Garaj-Vrhovac V et al. (2011): Assessment of cytogenetic damage and oxidative stress in personnel occupationally exposed to the pulsed microwave radiation of marine radar equipment
Esmekaya MA et al. (2011): Mutagenic and morphologic impacts of 1.8 GHz radiofrequency radiation on human peripheral blood lymphocytes (hPBLs) and possible protective role of pre-treatment with Ginkgo biloba (EGb 761)
Gurbuz N et al. (2010): Is There Any Possible Genotoxic Effect in Exfoliated Bladder Cells of Rat Under the Exposure of 1800 MHz GSM-Like Modulated Radio Frequency Radiation (RFR)?
Vijayalaxmi et al. (2009): Genetic damage in mammalian somatic cells exposed to extremely low frequency electro-magnetic fields: a meta-analysis of data from 87 publications (1990-2007)
Maes A et al. (2006): Cytogenetic investigation of subjects professionally exposed to radiofrequency radiation
Gandhi G et al. (2005): Genetic damage in mobile phone users: some preliminary findings
Lalic H et al. (2001): Comparison of chromosome aberrations in peripheral blood lymphocytes from people occupationally exposed to ionizing and radiofrequency radiation
Garaj-Vrhovac V (1999): Micronucleus assay and lymphocyte mitotic activity in risk assessment of occupational exposure to microwave radiation
Maes A et al. (1995): Cytogenetic Effects of Microwaves from Mobile Communication Frequencies (954 MHz)
Garaj-Vrhovac V et al. (1993): The rate of elimination of chromosomal aberrations after accidental exposure to microwave radiation
Garson OM et al. (1991): A chromosomal study of workers with long-term exposure to radio-frequency radiation
Garaj-Vrhovac V et al. (1990): Comparison of chromosome aberration and micronucleus induction in human lymphocytes after occupational exposure to vinyl chloride monomer and microwave radiation