The authors used microdialysis to study acetylcholine (ACh) release in the hippocampus of freely moving rats after acute irradiation with two radiofrequency fields, using power density under permissible levels.
Modulation type: CW
Exposure duration: continuous for 1 h
Modulation type: AM
Exposure duration: continuous for 1 or 14 h
|Distance between exposed object and exposure source||60 cm|
|Chamber||The rats were placed individually in a narrow Teflon cage (W 15 cm x L 30 cm x H 30 cm) with their main body axis parallel to the magnetic component of the field.|
|Setup||The cage was positioned with its input face at 60 cm from the antenna and its bottom 5 cm under the axis.|
|Sham exposure||A sham exposure was conducted.|
|Additional info||The rectangular horn antennas had a horizontal great axis, so they emitted a horizontal magnetic component and a vertical electric component.|
|Modulation frequency||32 Hz|
[Kunjilwar and Behari, 1993]
After exposure to 2.45 GHz radiofrequency, rats exposed at 2 mW/cm² did not show a significant modification of ACh release, whereas those exposed at 4 mW/cm² showed a significant 40% decrease in mean ACh release (this decrease was maximal at 5h post exposure). Irradiation to the 800 MHz radiofrequency for 1 h did not cause any significant effect, but exposure for 14 hours induced a significant 43% decrease in ACh release during the period 11 p.m.-4 a.m. compared to control rats. In the control group the authors observed an increase of ACh release at the beginning of the night, which was linked to the waking period of rats. The results indicate that neurochemical modification of the hippocampal cholinergic system can be observed during and after an exposure to low intensity radiofrequency.