Study type: Medical/biological study (experimental study)

The effect of microwave radiation on the cell genome. med./bio.

Published in: Mutation Research - Letters 1990; 243 (3): 87-93

Aim of study (acc. to editor)

To study the effect of microwave radiation on the incorporation of [³H]thymidine and on the incidence and the frequency of structural chromosome aberrations.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 7.7 GHz
Exposure duration: 15, 30 or 60 min

Exposure 1

Main characteristics
Frequency 7.7 GHz
Type
Waveform
Exposure duration 15, 30 or 60 min
Exposure setup
Exposure source
Setup samples placed below the horn antenna on a thin bakelite plate (1.2 m high).
Additional info slit of the horn antenna was 80 cm.
Parameters
Measurand Value Type Method Mass Remarks
power density 300 W/m² unspecified measured - -
power 2 W - cf. remarks - max output of the generator

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results suggest that microwave radiation causes changes in the synthesis as well as in the structure of DNA molecules. The inhibition of [³H]thymidine incorporation took place by complete prevention of DNA from entering into the S phase. The normal rate of [³H]thymidine was recovered within 1 generation cycle. Mutagenic tests showed that even DNA macromolecules were involved in the process. In comparison with the control samples there was a higher frequency of specific chromosome lesions in cells that had been exposed.

Study character:

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