Study type: Medical/biological study (experimental study)

Acute exposure to 50 Hz magnetic fields with harmonics and transient components: Lack of effects on nighttime hormonal secretion in men. med./bio.

Published in: Bioelectromagnetics 2003; 24 (1): 12-20

Aim of study (acc. to author)

The effects of exposure of subjects to a 50 Hz and intermediate frequency magnetic field on the nighttime blood plasma levels of melatonin and other hormones should be investigated.

Background/further details

10 male subjects participated in the study and each attended 3 night sessions (but only samples from 9 subjects were analyzed). The first session was for habituation to the experimental conditions, the other 2 sessions were for exposure or sham exposure, respectively, with the order being unknown to the subjects.
Blood samples were automatically collected every hour during exposure and sham exposure in general and every 10 minutes between 22.00 and 02.00 o'clock.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz–1 kHz
Exposure duration: continuous for 12 h (20.00 to 08.00 o'clock)

Exposure 1

Main characteristics
Frequency 50 Hz–1 kHz
Type
Waveform
Polarization
Exposure duration continuous for 12 h (20.00 to 08.00 o'clock)
Additional info the following components were superimposed on the primary 50 Hz field: third harmonics with 30% intensity of primary field (effective value) fifth harmonics with 10% intensity of the primary field (effective value) 1 kHz with initial 100 µT (peak) field, which attenuated exponentially over a duration of 50 ms and repeated at 1 s intervalls (1 burst/s)
Exposure setup
Exposure source
Chamber the exposure room had a dual structure with an inner room (cube with 2.7 m side length) being completely enclosed within a larger outer room (cube with 4 m side length); frame for room was made of wood; interior resembled a small room of a house with textured walls, equipped with a small table and a bed
Setup 4 coil-square loop configuration with 3-axis Merritt coils; the outer two coils had 16 turns each and the inner coils had 8 turns; coils were located in the space between the inner and outer rooms; the coils were set in the same manner in each of the three dimensions of the room except that the horizontal inner coils were wound around the door; all of the windings were formed with a twisted pair of copper wires; temperature was maintained at ± 1°C and relative humidity at ± 5%; room was not shielded from intruding fields; direction of the field coincided with the longer axis of the bed
Sham exposure A sham exposure was conducted.
Additional info sham exposure conditions were set by changing the current direction in one of the pair of wires of the coil
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 20 µT - measured - for the 50 Hz field
magnetic flux density 100 µT peak value measured - initial value of the 1 kHz field

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

All hormones showed time-dependent variabilities in their concentrations over the investigation period, which corresponded to typical physiological rhythms. However, no significant differences were found between exposure and sham exposure conditions.
The authors conclude that exposure of subjects to a 50 Hz and intermediate frequency magnetic field shows no effects on the nighttime blood plasma levels of melatonin and other hormones.

Study character:

Study funded by

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