Medical/biological study (experimental study)

Effect of radiofrequency radiation on mRNA expression in cultured rodent cells med./bio.

By: Parker JE, Kiel JL, Winters WD

Published in: Physiol Chem Phys Med NMR 1988; 20 (2): 129-134

To study if changes at the level of mRNA expression could be detected after microwave exposure of cultured rodent cells.

mRNA expression of certain oncogenes, heat shock proteins, and the long terminal repeat (LTR) region of mouse mammary tumor virus in four rodent cells lines was investigated. All cells were exposed to microwaves at temperatures of 37°, 40°, 42° and 45°C.

Exposure	Parameters
Exposure 1: 2.45 GHz Modulation type: CW Exposure duration: 3, 5, 10, 15 and 20 min	SAR: 103.5 mW/g mean (unspecified) (+/- 4.2 W/kg.)

Frequency	2.45 GHz
Charakteristic	guided field
Exposure duration	3, 5, 10, 15 and 20 min
Additional info	Reference Article on wave guide apparatus: Kiel, J., and Erwin, D.(1984) Physiological Chemistry and Physics and Medical NMR 16, 317-323.

Modulation type	CW

Exposure source	circular waveguide
Setup	nitrocellulose tube (16 mm x 76 mm) kept in the waveguide.
Additional info	Cells were exposed to microwaves at 37°C, 40°C, 42°C and 45°C.

Measurand	Value	Type	Method	Mass	Remarks
SAR	103.5 mW/g	mean	unspecified	unspecified	+/- 4.2 W/kg.

Exposed system:

Investigated system:

Time of investigation:

In this study no significant differences in mRNA expression were observed after microwave exposure.

Study character:

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