Study type: Medical/biological study (experimental study)

Effect of radiofrequency radiation on mRNA expression in cultured rodent cells. med./bio.

Published in: Physiol Chem Phys Med NMR 1988; 20 (2): 129-134

Aim of study (acc. to author)

To study if changes at the level of mRNA expression could be detected after microwave exposure of cultured rodent cells.

Background/further details

mRNA expression of certain oncogenes, heat shock proteins, and the long terminal repeat (LTR) region of mouse mammary tumor virus in four rodent cells lines was investigated. All cells were exposed to microwaves at temperatures of 37°, 40°, 42° and 45°C.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: 3, 5, 10, 15 and 20 min
  • SAR: 103.5 mW/g mean (unspecified) (+/- 4.2 W/kg.)

Exposure 1

Main characteristics
Frequency 2.45 GHz
Charakteristic
  • guided field
Exposure duration 3, 5, 10, 15 and 20 min
Additional info Reference Article on wave guide apparatus: Kiel, J., and Erwin, D.(1984) Physiological Chemistry and Physics and Medical NMR 16, 317-323.
Modulation
Modulation type CW
Exposure setup
Exposure source
Setup nitrocellulose tube (16 mm x 76 mm) kept in the waveguide.
Additional info Cells were exposed to microwaves at 37°C, 40°C, 42°C and 45°C.
Parameters
Measurand Value Type Method Mass Remarks
SAR 103.5 mW/g mean unspecified unspecified +/- 4.2 W/kg.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In this study no significant differences in mRNA expression were observed after microwave exposure.

Study character:

Study funded by