Study type: Medical/biological study (experimental study)

Effect of low-level microwave irradiation on the duodenal electrical activity of the unanesthetized rat med./bio.

By: Santini R
Published in: J Microw Power 1982; 17 (4): 329-334
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Aim of study (acc. to author)

To investigate the effects of a low level 2450 MHz microwave exposure on duodenal electrical activity in rats.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: 1-4 h
Exposure 2: 2.45 GHz
Exposure duration: 1-4 h

Exposure 1

Main characteristics
Frequency 2.45 GHz
Exposure duration 1-4 h
Exposure setup
Exposure source
Chamber Plexiglass cage/ 20 cm x 10 cm x 12 cm
Additional info Anaesthesized Wistar rats were implanted with three chrome nickel insulated electrodes (120 µm, 90 cm in length) in the duodenal wall 2 mm apart and 2 cm from the pylorus.
Parameters
Measurand Value Type Method Mass Remarks
power density 50 W/m² unspecified measured - -
SAR 5.35 mW/g unspecified measured - -

Exposure 2

Main characteristics
Frequency 2.45 GHz
Exposure duration 1-4 h
Exposure setup
Exposure source
Chamber Plexiglass cage/ 20 cm x 10 cm x 12 cm
Additional info Anaesthesized Wistar rats were implanted with three chrome nickel insulated electrodes (120 µm, 90 cm in length) in the duodenal wall 2 mm apart and 2 cm from the pylorus.
Parameters
Measurand Value Type Method Mass Remarks
SAR 6.05 mW/g unspecified measured - -
power density 75 W/m² unspecified measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
  • duodenum
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The duodenal electric activity is characterized by two types of potentials: action potentials (spikes) and slow waves (basal electric rhythm and pacemaker potential). The obtained results showed that microwave exposure ususally leads to an accelerating effect on slow waves, and a specific inhibitory effect on action potentials. Both effects appear to be directly dependent on the SAR values.

Study character:

Study funded by