Study type: Therapeutical study (experimental study)

Low power millimeter wave irradiation exerts no harmful effect on human keratinocytes in vitro. med./bio.

Published in: Bioelectromagnetics 2003; 24 (3): 165-173

Aim of study (acc. to author)

In order to learn more about potential risk factors of low power millimeter waves, the in vitro effect of millimeter wave irradiation on epidermal keratinocytes by measuring chemokine release, heat shock protein production, determining cell viability, and gap junctional intercellular communication were studied.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 61.2 GHz
Modulation type: CW
Exposure duration: 30 or 60 min
Exposure 2: 42.25 GHz
Modulation type: CW
Exposure duration: 30 or 60 min

Exposure 1

Main characteristics
Frequency 61.2 GHz
Type
Exposure duration 30 or 60 min
Additional info ± 2.1 GHz
Modulation
Modulation type CW
Exposure setup
Exposure source
  • millimetr wave generator
Additional info Control plates with keratinocytes were either kept at 37°C for 60 min (negative control), or incubated at 43°C for the same period of time (positive control)
Parameters
Measurand Value Type Method Mass Remarks
power density 29 mW/cm² - calculated - ± 2 mW/cm²
SAR 770 W/kg - calculated - ± 42 W/kg

Exposure 2

Main characteristics
Frequency 42.25 GHz
Type
Exposure duration 30 or 60 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Setup 2.6 mm x 5.2 mm waveguide centered over the bottom of the culture dish
Parameters
Measurand Value Type Method Mass Remarks
power density 1.67 W/cm² - - - -
SAR 37 W/kg - calculated - +/- 3 W/kg

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

No harmful effect of low power millimeter waves irradiation on both keratinocyte function and structure in vitro was detected. The data support the contention that low power millimeter waves irradiation in clinical practice is safe and without risk of induction of topical inflammatory reactions or cell damage in epidermal keratinocytes.

Study character:

Study funded by

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