Enzymology. A subfamily of mitogen-activated protein kinase that plays an important role in signal transduction and in cellular processes such as regulation of mitosis, meiosis, and cell differentiation. The extracellular signal regulated MAP kinases are regulated by a broad variety of cell surface receptors and can be activated by certain carcinogens. There are several isoforms, called ERK-1, ERK-2 and so on.
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