Study type: Medical/biological study (experimental study)

ELF Magnetic Field Effects On Some Hematological And Biochemical Parameters Of Peripheral Blood In Mice. med./bio.

Published in: Electro Magnetobiol 2001; 20 (2): 185-191

Aim of study (acc. to author)

The effects of a chronic exposure of mice to a 60 Hz magnetic field on hematologic parameters should be investigated.

Background/further details

The mice were split into the following groups (n=20 each): exposure to the magnetic field for 1) 1 month, 2) 6 months, 3) 8 months and 4) a control group (remark EMF-Portal: it is not stated when the control group was investigated). Further remark EMF-Portal: In the discussion, it is stated that 10 mice died after 6 months, although the histological analysis after 8 months was conducted with all rats.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 60 Hz
Exposure duration: continuous (?) for 1 month, 6 months or 8 months

Exposure 1

Main characteristics
Frequency 60 Hz
Type
Waveform
Exposure duration continuous (?) for 1 month, 6 months or 8 months
Exposure setup
Exposure source
Chamber 48 cm x 24 cm x 14 cm plastic cages
Setup exposure system consisted of two parallel horizontal flat circular coils (0.65 m radius, 0.65 m distance) with a common axis; MF was perpendicular to the N-S static geomagnetic field; temperature was 23 ± 2°C and relative humidity was 65%
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 110 µT - measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In the hematologic parameters, the hematocrit, hemoglobin, neutrophils and leukocytes levels were significantly decreased and the lymphocytes level significantly increased in the exposure group compared to the control group after 6 months.
In the biochemical parameters, the total protein content was significantly decreased after 6 months in the exposure group compared to the control group. After 8 months, the chloride level was significantly increased and the levels of calcium, glucose and total protein were significantly decreased in exposed animals compared to the control group.
The weights of liver and spleen of exposed animals were significantly higher in all exposure groups compared to the control group.
The authors conclude that a chronic exposure of mice to a 60 Hz magnetic field could influence some hematologic parameters and the weight of liver and spleen.

Study character:

Related articles