この研究は、Balb/Cマウスを用いて、超低周波磁界（ELF-MF）への慢性ばく露（1、6、および8か月）が、末梢血の血液学的および生化学的パラメータ、ならびに肝臓および脾臓の組織学的所見に影響を与えるか否かを調べた。マウスは、ヘルムホルツコイルシステムで生成された0.11 mT、60 Hzの正弦波磁界にばく露した。その結果、実験したばく露期間において、ELF-MFとがんとの関連は観察されなかった；ただし、白血球減少、ヘモグロビン減少、および肝臓と脾臓の重量増加が観察された、と報告している。
The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →
The effects of a chronic exposure of mice to a 60 Hz magnetic field on hematologic parameters should be investigated.
The mice were split into the following groups (n=20 each): exposure to the magnetic field for 1) 1 month, 2) 6 months, 3) 8 months and 4) a control group (remark EMF-Portal: it is not stated when the control group was investigated). Further remark EMF-Portal: In the discussion, it is stated that 10 mice died after 6 months, although the histological analysis after 8 months was conducted with all rats.
|ばく露時間||continuous (?) for 1 month, 6 months or 8 months|
|チャンバの詳細||48 cm x 24 cm x 14 cm plastic cages|
|ばく露装置の詳細||exposure system consisted of two parallel horizontal flat circular coils (0.65 m radius, 0.65 m distance) with a common axis; MF was perpendicular to the N-S static geomagnetic field; temperature was 23 ± 2°C and relative humidity was 65%|
In the hematologic parameters, the hematocrit, hemoglobin, neutrophils and leukocytes levels were significantly decreased and the lymphocytes level significantly increased in the exposure group compared to the control group after 6 months.
In the biochemical parameters, the total protein content was significantly decreased after 6 months in the exposure group compared to the control group. After 8 months, the chloride level was significantly increased and the levels of calcium, glucose and total protein were significantly decreased in exposed animals compared to the control group.
The weights of liver and spleen of exposed animals were significantly higher in all exposure groups compared to the control group.
The authors conclude that a chronic exposure of mice to a 60 Hz magnetic field could influence some hematologic parameters and the weight of liver and spleen.