研究のタイプ: 医学/生物学の研究 (experimental study)

[マウスの末梢血の血液および生化学的パラメータに対するELF磁界の影響] med./bio.

ELF Magnetic Field Effects On Some Hematological And Biochemical Parameters Of Peripheral Blood In Mice.

掲載誌: Electro Magnetobiol 2001; 20 (2): 185-191

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研究目的(著者による)

The effects of a chronic exposure of mice to a 60 Hz magnetic field on hematologic parameters should be investigated.

詳細情報

The mice were split into the following groups (n=20 each): exposure to the magnetic field for 1) 1 month, 2) 6 months, 3) 8 months and 4) a control group (remark EMF-Portal: it is not stated when the control group was investigated). Further remark EMF-Portal: In the discussion, it is stated that 10 mice died after 6 months, although the histological analysis after 8 months was conducted with all rats.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 60 Hz
ばく露時間: continuous (?) for 1 month, 6 months or 8 months

ばく露1

主たる特性
周波数 60 Hz
タイプ
  • magnetic field
波形
  • sinusoidal
ばく露時間 continuous (?) for 1 month, 6 months or 8 months
ばく露装置
ばく露の発生源/構造
チャンバの詳細 48 cm x 24 cm x 14 cm plastic cages
ばく露装置の詳細 exposure system consisted of two parallel horizontal flat circular coils (0.65 m radius, 0.65 m distance) with a common axis; MF was perpendicular to the N-S static geomagnetic field; temperature was 23 ± 2°C and relative humidity was 65%
パラメータ
測定量 種別 Method Mass 備考
磁束密度 110 µT - 測定値 - -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

In the hematologic parameters, the hematocrit, hemoglobin, neutrophils and leukocytes levels were significantly decreased and the lymphocytes level significantly increased in the exposure group compared to the control group after 6 months.
In the biochemical parameters, the total protein content was significantly decreased after 6 months in the exposure group compared to the control group. After 8 months, the chloride level was significantly increased and the levels of calcium, glucose and total protein were significantly decreased in exposed animals compared to the control group.
The weights of liver and spleen of exposed animals were significantly higher in all exposure groups compared to the control group.
The authors conclude that a chronic exposure of mice to a 60 Hz magnetic field could influence some hematologic parameters and the weight of liver and spleen.

研究の種別:

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