Study type: Medical/biological study (experimental study)

Radial arm maze performance of rats following repeated low level microwave radiation exposure. med./bio.

Published in: Bioelectromagnetics 2004; 25 (1): 49-57

Aim of study (acc. to author)

To examine possible changes in working memory of rats following whole body exposure to microwave irradiation.

Background/further details

Rats received a preexposure injection of one of three psychoactive compounds (physostigmine, naltrexone hydrochloride, naloxone methiodide) or saline, to determine whether a compound would interact with microwave irradiation to affect performance in the maze. The study was conducted as an attempt to confirm the results of a previous study (publication id 109).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: pulsed
Exposure duration: 45 min each on 10 testing days

Exposure 1

Main characteristics
Frequency 2.45 GHz
Exposure duration 45 min each on 10 testing days
Modulation
Modulation type pulsed
Pulse width 2 µs
Packets per second 500
Exposure setup
Exposure source
Chamber Plexiglass chamber
Setup waveguide constructed of galvanized wire screen in which a circularly polarized TE11 mode field configuration was realized
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 600 µW/g mean measured whole body Dewar flask calorimetry and differential power method.

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Analyzes of error rates revealed no significant irradiation effect, no significant drug effect and no significant interaction between the two factors. There was a significant difference in test days with repeated test-trial days, which indicates that learning was accomplished. There was no significant interaction of test day and the other two main factors. The results of the analyzes of time it took each rat to enter all of the 12 baited arms included no significant exposure effect, a significant drug effect, a significant test day effect, and a significant interaction between drug and test day factors.
The authors concluded that there is no evidence from the current study that exposure to microwave irradiation under these parameters caused decrements in the ability of rats to learn the spatial memory task. These findings and those of other studies of possible working memory changes show differing results.

Study character:

Study funded by

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