Study type: Medical/biological study (experimental study)

Influence of anesthesia on ocular effects and temperature in rabbit eyes exposed to microwaves med./bio.

By: Kojima M, Hata I, Wake K, Watanabe S, Yamanaka Y, Kamimura Y, Taki M, Sasaki K
Published in: Bioelectromagnetics 2004; 25 (3): 228-233
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Aim of study (acc. to author)

To clarify the influence of systemic anesthesia on ocular effects induced by 2.45 GHz microwave exposure in rabbits.

Background/further details

Rabbits were anaesthetized with ketamin hydrochlorid and xylazine.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: intermittent, 60 min exposed + 60 min cooling time + 60 min exposure

General information

The exposure was conducted on the eye either under anesthesia or without anesthesia.

Exposure 1

Main characteristics
Frequency 2.45 GHz
Exposure duration intermittent, 60 min exposed + 60 min cooling time + 60 min exposure
Modulation
Modulation type unspecified
Exposure setup
Exposure source
Distance between exposed object and exposure source 40 mm
Setup Two rabbits, anesthesized or non-anesthesized were exposed simultaneously and were fixed in a polycarbonate rabbit holder.
Parameters
Measurand Value Type Method Mass Remarks
power density 300 mW/cm² unspecified unspecified - at the corneal surface.
SAR 108 mW/g mean cf. remarks - SAR of the whole eye, SAR analyzed by FDTD method.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Miosis, conjunctival congestion, corneal endem, and an increase of the light scattering in the anterior shallow lense cortex were observed. These observed changes were much more pronounced in rabbits under systemic anaesthesia. The observed changes were much mor pronounced in the anaesthesied group. The changes dissapeared within a week. Ocular temperature was found to be 2-9°C higher in the anaesthezied rabbits.

Study character:

Study funded by

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