To study possible genotoxic effects of high peak-power pulsed electromagnetic fields on erythrocytes of the frog Xenopus laevis (South African male clawd toads).
| Exposure | Parameters |
|---|---|
|
Exposure 1:
8.8 GHz
Modulation type:
pulsed
Exposure duration:
continuous for 40 min
|
|
Ionization radiation exposure were conducted with the cells exposed to 0, 50, 100 and 200 cGy from 60Co gamma ray source
| Frequency | 8.8 GHz |
|---|---|
| Charakteristic |
|
| Exposure duration | continuous for 40 min |
| Modulation type | pulsed |
|---|---|
| Pulse width | 180 ns |
| Repetition frequency | 50 Hz |
| Exposure source |
|
|---|---|
| Setup | Fifty microliters of cell suspension (25±1°C at the beginning and 29±1°C at the end of the exposure) were exposed in special plastic cuvettes of cylindrical shape placed inside a rectangular wave guide at a distance of 25 to 30 mm from the wave guide. |
| Sham exposure | A sham exposure was conducted. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| electric field strength | 1,420 kV/m | maximum | - | - | - |
| SAR | 1.6 W/g | - | calculated | cf. remarks | calculated from temperature kinetic measurements |
| SAR | 300,000 kW/kg | peak value | - | - | - |
The temperature rise in the blood samples was 3.5 +/- 0.1°C. The results show that the increase in DNA damage after exposure of erythrocytes to high peak-power pulsed electromagnetic fields was induced by the rise in temperature in the irradiated cell suspension. This was confirmed in experiments in which blood samples were incubated for 40 min under the corresponding temperature conditions. The data allow the authors to conclude that high peak-power pulsed electromagnetic field-exposure at the given modality did not cause any athermal genotoxic effect on frog erythrocytes in vitro.
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