Study type: Medical/biological study (experimental study)

Effect of rotating electromagnetic fields on proteolytic activity of pepsin in rats. med./bio.

Published in: Bull Exp Biol Med 2004; 137 (6): 632-634

Aim of study (acc. to author)

To study the relationship between changes in proteolytic activity of pepsin and morphological characteristics of the gastric mucosa produced by nonthermal electromagnetic fields with the plane of polarization rotating in either right-handed or left-handed sense.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 37 GHz
Exposure duration: repeated daily exposure, 15 min/day for 6 days
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General information

Rats were divided into 3 groups (n=10 per group); group 1 was used as control, group 2 and group 3 were exposed to D-polarization and L-polarization respectively.

Exposure 1

Main characteristics
Frequency 37 GHz
Exposure duration repeated daily exposure, 15 min/day for 6 days
Exposure setup
Parameters

No parameters are specified for this exposure.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

D-polarization (right-handed) increased digestive activity of pepsin in relation to blood plasma proteins and hemoglobin. L-polarization (left-handed) suppressed pepsin production.
Morphological examination revealed progressive hypertrophy of glands and chief cells on days 1-6 of exposure to D-electromagnetic fields. These changes reflected high-intensity secretion of pepsin and HCl. L-electromagnetic irradiation induced morphological changes in the gastric mucosa (progressive necrobiotic changes).

Study character:

Study funded by

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