Study type: Medical/biological study (experimental study)

Influence of exposure to extremely low frequency magnetic field on neuroendocrine cells and hormones in stomach of rats. med./bio.

Published in: Korean J Physiol Pharmacol 2011; 15 (3): 137-142

Aim of study (acc. to author)

To study the effects of the exposure to extremely low frequency electromagnetic fields on gastric morphology and function in rats in connection with the development of chronic stress state.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 60 Hz
Exposure duration: continuous for 1 or 2 weeks

Exposure 1

Main characteristics
Frequency 60 Hz
Type
Exposure duration continuous for 1 or 2 weeks
Exposure setup
Exposure source
Setup 1 m square Helmholtz coils in a wooden frame; winding of 200 turns for each coil split in half for allowing the current to flow in the same sense through each half of the winding (field aiding); coils mounted on a platform; animal cage placed in the center of the coil system
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.1 mT - measured - in the center of the coils

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated material:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The exposure to extremely low frequency magnetic fields altered the distribution and occurrence of gastrin- (increase), ghrelin- (decrease) and somatostatin- (decrease) positive endocrine cells in the stomach of rats. However, the secretion of those hormones into the blood from endocrine cells did not change significantly with exposure.
Comparing with sham exposure, extremely low frequency magnetic field exposure for one and two weeks induced an increase in BaSO4 suspension propelling ratio of gastrointestinal tract, indicating that extremely low frequency magnetic field affects gastrointestinal motility.
The data revealed that extremely low frequency magnetic field exposure might influence the activity of endocrine cells, an important element of the intrinsic regulatory system in the digestive tract.

Study character:

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