Study type: Medical/biological study (experimental study)

Different effects of chronic exposure to ELF magnetic field on spontaneous and amphetamine-induced locomotor and stereotypic activities in rats. med./bio.

Published in: Brain Res Bull 2005; 67 (6): 498-503

Aim of study (acc. to author)

To study the effects of chronic exposure to an extremely low frequency magnetic field on spontaneous and amphetamine-induced (1.5 mg/kg) locomotor and stereotypic activities in rats on exposure days 1, 3, and 7 (test session = 2 h).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuously for 7 days except 120 (on day 1, 3, and 7) min for test sessions

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuously for 7 days except 120 (on day 1, 3, and 7) min for test sessions
Exposure setup
Exposure source
Distance between exposed object and exposure source 20 cm
Setup Two groups of three rats were simultaneously exposed in their plastic cages which were located 20 cm from the poles. Sham exposed animals were kept in a non activated exposure system.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.5 mT mean measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The main findings of the study are:
1) the enhancement of spontaneous locomotor activity after 1-day exposure to extremely low frequency magnetic field;
2) the attenuation of amphetamine-induced locomotor activity after 7 days of irradiation;
and 3) the attenuation of amphetamine-induced stereotypic activity independently of exposure duration.

Study character:

Study funded by

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