Study type: Medical/biological study (experimental study)

Experimental studies of brain tumour development during exposure to continuous and pulsed 915 MHz radiofrequency radiation. med./bio.

Published in: Bioelectrochem Bioenerg 1993; 30: 313-318

Aim of study (acc. to editor)

To investigate the effects of electromagnetic field exposure in a rat brain glioma model.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 915 MHz
Modulation type: CW
Exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 10-15 days
Exposure 2: 915 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 10 days
  • power: 2 W peak value
  • SAR: 0.0077 W/kg
Exposure 3: 915 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 10 days
Exposure 4: 915 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 13 days
Exposure 5: 915 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 9 days
Exposure 6: 915 MHz
Modulation type: pulsed
Exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 9-13 days

Exposure 1

Main characteristics
Frequency 915 MHz
Type
Charakteristic
  • guided field
Exposure duration repeated daily exposure, 7 h/day, 5 days/week, for 10-15 days
Modulation
Modulation type CW
Exposure setup
Exposure source
Setup Unanaesthetized animals were exposed in well ventilated TEM cells for 7 h per day with a 30-min break after 4 h for feeding and stretching.
Sham exposure A sham exposure was conducted.
Additional info Control animals were kept in identical TEM cells without EMF exposure.
Parameters
Measurand Value Type Method Mass Remarks
power 1 W peak value - - -
SAR 1.67 W/kg - - - -

Exposure 2

Main characteristics
Frequency 915 MHz
Type
Charakteristic
  • guided field
Exposure duration repeated daily exposure, 7 h/day, 5 days/week, for 10 days
Modulation
Modulation type pulsed
Pulse width 0.57 ms
Duty cycle 0.2 %
Repetition frequency 4 Hz
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power 2 W peak value - - -
SAR 0.0077 W/kg - - - -

Exposure 3

Main characteristics
Frequency 915 MHz
Type
Charakteristic
  • guided field
Exposure duration repeated daily exposure, 7 h/day, 5 days/week, for 10 days
Modulation
Modulation type pulsed
Pulse width 0.57 ms
Duty cycle 0.5 %
Repetition frequency 8.33 Hz
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power 2 W peak value - - -
SAR 0.016 W/kg - - - -

Exposure 4

Main characteristics
Frequency 915 MHz
Type
Charakteristic
  • guided field
Exposure duration repeated daily exposure, 7 h/day, 5 days/week, for 13 days
Modulation
Modulation type pulsed
Pulse width 0.57 ms
Duty cycle 0.9 %
Repetition frequency 16 Hz
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power 2 W peak value - - -
SAR 0.03 W/kg - - - -

Exposure 5

Main characteristics
Frequency 915 MHz
Type
Charakteristic
  • guided field
Exposure duration repeated daily exposure, 7 h/day, 5 days/week, for 9 days
Modulation
Modulation type pulsed
Pulse width 0.57 ms
Duty cycle 12 %
Repetition frequency 217 Hz
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power 2 W peak value - - -
SAR 0.4 W/kg - - - -

Exposure 6

Main characteristics
Frequency 915 MHz
Type
Charakteristic
  • guided field
Exposure duration repeated daily exposure, 7 h/day, 5 days/week, for 9-13 days
Modulation
Modulation type pulsed
Pulse width 6 ms
Duty cycle 30 %
Repetition frequency 50 Hz
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power 2 W peak value - - -
SAR 1 W/kg - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The results does not show a significant difference in tumor size between animals exposed to 915 MHz microwaves, and those not exposed. The rectal temperature recorded before, at 4h and directly after exposure did not fall or rise.

Study character:

Study funded by

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