Study type: Medical/biological study (experimental study)

Proteomic response of Schizosaccharomyces pombe to static and oscillating extremely low-frequency electromagnetic fields. med./bio.

Published in: Proteomics 2006; 6 (17): 4755-4764

Aim of study (acc. to author)

To study the effects of static and oscillating extremely low frequency electromagnetic fields on the proteomes of wild type yeast Schizosaccharomyces pombe and a deletion mutant which displays increased sensitivity to a variety of cellular stresses.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Exposure duration: continuous for 60 min
Exposure 2: 50 Hz
Exposure duration: continuous for 60 min

Exposure 1

Main characteristics
Frequency
Type
Exposure duration continuous for 60 min
Exposure setup
Exposure source
Setup Four 100 ml conical flasks were placed in the gap provided by the coils where the MF was almost uniform. The currents in the coils were passed in opposite direction to get no MF for sham exposure.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 1 mT unspecified measured - -

Exposure 2

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration continuous for 60 min
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 1 mT unspecified measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Whilst the data identified a number of protein isoforms that displayed significant differential expression across experimental conditions, there was no correlation between their patterns of expression and the extremely low frequency electromagnetic field exposure. The authors conclude that there are no significant effects of either static or oscillating electromagnetic fields on the yeast proteome (the authors hypothesise that the proteins identified must be sensitive to subtle changes in culture and/or handling conditions).

Study character:

Study funded by

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