Study type: Medical/biological study (experimental study)

Lack of a co-promoting effect of a 60 Hz magnetic field on skin tumorigenesis in SENCAR mice med./bio.

By: Sasser LB, Anderson LE, Morris JE, Miller DL, Walborg Jr EF, Kavet R, Johnston DA, DiGiovanni J
Published in: Carcinogenesis 1998; 19 (9): 1617-1621
Download citation in RIS format

Aim of study (acc. to author)

To examine a possible co-promoting effect of an extremely low frequency magnetic field (ELF EMF) exposure of chemical induced skin tumorigenesis of mice.

Background/further details

Tumor incidence an multipicity were investigated weekly for 23 weeks. Each mice obtained a subcarcinogenic dose of DMBA (10 nmol). Two weeks after DMBA administration, mice were treated with TPA (0.85, 1.7, or 3.4 nmol respectively) twice a week.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 60 Hz
Exposure duration: 6 h/day, 5 days/week, for 23 weeks

Exposure 1

Main characteristics
Frequency 60 Hz
Type
Waveform
Polarization
Exposure duration 6 h/day, 5 days/week, for 23 weeks
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 2 mT mean measured - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

No significant effects on tumor incidence or tumor multiplicity were found by 2 mT magnetic field exposure.

Study character:

Study funded by

Related articles