The protein transthyretin served as marker of alterations of the blood-cerebrospinal fluid barrier. The same study population as in publication 16510 was used. The participants were asked to answer a questionnaire and to leave a blood sample.
|Group 1||mobile phone and DECT phone use|
|Group 2||mobile phone use|
|Group 3||analog mobile phone use|
|Group 4||digital mobile phone use|
|Group 5||UMTS mobile phone use|
|Group 6||DECT phone use|
|Group 7||cumulative use of mobile phone and DECT phone in hours|
|Group 8||years since first use of mobile phone and DECT phone|
|Group 9||minutes of use on the day of giving blood, mobile phones|
|Group 10||minutes of use on the day of giving blood, DECT|
|Group 11||minutes from last use until blood sampling, mobile phones and DECT|
|Participation rate||31 %|
Logistic regression analysis of serum transthyretin on mobile phone and DECT phone use yielded increased odds ratios that were statistically not significant (OR 1.2, CI 0.6-2.4). Linear regression analysis of time since first use gave significant findings for men having used analog mobile phones or mobile and DECT phone combined, but not for women. Regarding short-term use, significantly higher serum transthyretin concentrations were observed in women the sooner the blood was withdrawn after the most recent telephone call on that day.
Limitations of the study are the low participation rate and exposure assessment by questionnaire. Serum transthyretin is a marker of nutritional status, thus malnutrition could possibly confound the results. The transthyretin level should ideally be analyzed in the cerebrospinal fluid which is not possible for ethical reasons.