Study type: Medical/biological study (experimental study)

Effect of whole-body exposure to high-frequency electromagnetic field on the brain cortical and hippocampal activity in mouse experimental model. med./bio.

Published in: Neuroquantology 2007; 5 (3): 292-303

Aim of study (acc. to author)

To study brain cortical and hippocampal activity during exposure to a radiofrequency electromagnetic field, similar to the range used by mobile phones.

Background/further details

It was hypothesized that some brain structures in Lurcher mutant mice should be more sensitive to stimulation with radiofrequency electromagnetic fields as these mice represent a model of neurodegenerative diseases. 20 adult Lurcher mutant mice and 20 healthy wild type mice (control) were exposed. Brain activity was recorded under anesthesia.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 880–890 MHz
Exposure duration: continuous for 40 min

Exposure 1

Main characteristics
Frequency 880–890 MHz
Type
Exposure duration continuous for 40 min
Exposure setup
Exposure source
Chamber Faraday's chamber
Parameters
Measurand Value Type Method Mass Remarks
power 10 W - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • before exposure
  • during exposure

Main outcome of study (acc. to author)

Under exposure, the electrocorticogram evaluation showed a shift towards low frequency components with clear effects in wild type mice and only gentle differences between frequency spectra in Lurcher mutant mice. Measurement of hippocampal rhythmicity showed gentle changes with increase of high frequencies as well as changes of theta wave activity in both groups.
The results support the idea of a different vulnerability of the central nervous system in mice with neurodefective brain to the influence of radiofrequency electromagnetic fields in comparison with controls.

Study character:

Study funded by

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