Study type: Medical/biological study (experimental study)

The influence of low power microwave on the properties of DPPC vesicles. med./bio.

Published in: Phys Med 2012; 28 (1): 48-53

Aim of study (acc. to author)

To study the effect of low power microwaves (950 MHz) on some structural and functional properties of liposomes which represent a good cell membrane model. The main objective was to eliminate the heat effect, as claimed by many authors to be the only effect of microwaves.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 950 MHz
Exposure duration: continuous for 1 and 2 hours

Exposure 1

Main characteristics
Frequency 950 MHz
Type
Exposure duration continuous for 1 and 2 hours
Exposure setup
Exposure source
Setup microwave generator with a horn antenna used; no further details given
Parameters
Measurand Value Type Method Mass Remarks
power density 2.5 mW/cm² - - - -

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • after exposure

Main outcome of study (acc. to author)

The amount of detergent needed to completely solubilize the liposomal membrane was increased after microwave exposure of liposomes, indicating an increased membrane resistance to the detergent and hence a change in the natural membrane permeation properties.
The data of the FTIR spectroscopy showed spectral changes in the exposed liposome preparations probably due to water loss and molecular conformational changes.
The flow activation energy measurements showed, that low power microwave exposure induced changes in the liposomes deformability (liposome fluidity was decreased and liposome rigidity was increased).
The authors conclude that low power microwaves of 950 MHz induced structural and functional changes in liposomes.

Study character:

Study funded by

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