研究のタイプ: 医学/生物学の研究 (experimental study)

[DPPC小胞の特性に対する低出力マイクロ波の影響] med./bio.

The influence of low power microwave on the properties of DPPC vesicles.

掲載誌: Phys Med 2012; 28 (1): 48-53

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研究目的(著者による)

To study the effect of low power microwaves (950 MHz) on some structural and functional properties of liposomes which represent a good cell membrane model. The main objective was to eliminate the heat effect, as claimed by many authors to be the only effect of microwaves.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 950 MHz
ばく露時間: continuous for 1 and 2 hours

ばく露1

主たる特性
周波数 950 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 1 and 2 hours
ばく露装置
ばく露の発生源/構造
ばく露装置の詳細 microwave generator with a horn antenna used; no further details given
パラメータ
測定量 種別 Method Mass 備考
電力密度 2.5 mW/cm² - - - -

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露前
  • ばく露後

研究の主なアウトカム(著者による)

The amount of detergent needed to completely solubilize the liposomal membrane was increased after microwave exposure of liposomes, indicating an increased membrane resistance to the detergent and hence a change in the natural membrane permeation properties.
The data of the FTIR spectroscopy showed spectral changes in the exposed liposome preparations probably due to water loss and molecular conformational changes.
The flow activation energy measurements showed, that low power microwave exposure induced changes in the liposomes deformability (liposome fluidity was decreased and liposome rigidity was increased).
The authors conclude that low power microwaves of 950 MHz induced structural and functional changes in liposomes.

研究の種別:

研究助成

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