RFID application is used for temperature measurement of stored blood products to support the decision of discarding or further using a blood product.
16 red blood cell units were stored at 4±2°C for 42 days. 12 units were used as control samples and 4 units were used as test samples (exposure).
Exposure duration: continuous for 42 days
|Exposure duration||continuous for 42 days|
|Chamber||410 cm x 350 cm x 280 cm cold storage room with an ambient temperature of 4±2°C|
|Setup||RFID system consisting of a semiactive RFID tag on the blood sample bag and a RFID reader-writer; operating distance 0 - 120 mm; experiments done in the cold storage room|
|Sham exposure||A sham exposure was conducted.|
In both groups glucose and pH levels decreased while lactate, free hemoglobin, and potassium increased within the expected levels. The hemolysis rate showed an increase after the 25th day in both groups (with slightly higher values in the exposed samples) but remained below the maximum acceptable limit value of 0.8%. Significant differences between exposure and control groups were observed in the levels of hemoglobin and hematocrit on day 7, pH on days 14, 21, and 28, and lactate on days 28 and 35, but during the whole study biochemical changes in all samples remained within the normal expected values.
In conclusion, all variables measured remained within the acceptable limits in both groups, without detecting any obvious adverse effects of RFID on red blood cells; therefore, one can conclude that it is feasible to implement RFID-enabled processes.